this bug has existed in the game for a really long time now, and usually happens when you run Papulatus on multiple characters. Restarting the game fixes it and you should be ok for a couple clears before it starts getting loose again.
It seems that GMS copy-pasted MSEA hp (10.5b -> 140b).
This is the same as Chaos CQueen in GMS (without as much pdr, but still) but with a negligible boss crystal price.